Oxprenolol
Title: Oxprenolol
CAS Registry Number: 6452-71-7
CAS Name: 1-[(1-Methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-2-propanol
Additional Names: 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-2-propanol; 1-(isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane
Molecular Formula: C15H23NO3
Molecular Weight: 265.35
Percent Composition: C 67.90%, H 8.74%, N 5.28%, O 18.09%
Literature References: b-Adrenergic blocker. Prepn: BE 669402 (1966 to Ciba), C.A. 65, 5402d (1966), corresp to GB 1077603. Metabolic studies: Garteiz, J. Pharmacol. Exp. Ther. 179, 354 (1971). Crystal structure of hydrochloride: J. M. Leger et al., Acta Crystallogr. 33B, 2156 (1977). Long-term prevention study in coronary heart disease: S. H. Taylor et al., N. Engl. J. Med. 307, 1293 (1982).
Properties: Crystals from hexane, mp 78-80°.
Melting point: mp 78-80°
 
Derivative Type: Hydrochloride
CAS Registry Number: 6452-73-9
Manufacturers' Codes: Ba-39089
Trademarks: Coretal (Polfa); Laracor (Lagap); Paritane (Berk); Trasicor (Novartis); Trasacor (Novartis)
Molecular Formula: C15H23NO3.HCl
Molecular Weight: 301.81
Percent Composition: C 59.69%, H 8.02%, N 4.64%, O 15.90%, Cl 11.75%
Properties: Crystals, mp 107-109°.
Melting point: mp 107-109°
 
Therap-Cat: Antihypertensive, antianginal, antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic; Antihypertensive; Aryloxypropanolamine Derivatives.

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