Perazine
Title: Perazine
CAS Registry Number: 84-97-9
CAS Name: 10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine
Additional Names: N-methylpiperazinyl-N¢-propylphenothiazine; 10-(g-methylpiperazinopropyl)phenothiazine
Manufacturers' Codes: P-725
Trademarks: Taxilan
Molecular Formula: C20H25N3S
Molecular Weight: 339.50
Percent Composition: C 70.76%, H 7.42%, N 12.38%, S 9.44%
Literature References: Prepn: Hromatka et al., Monatsh. Chem. 88, 56, 193 (1957); 91, 107 (1960); Horclois, GB 780193 (1957 to Rhône-Poulenc).
Properties: Crystals, mp 51-53°. bp0.001 160-170° (air bath temp).
Melting point: mp 51-53°
Boiling point: bp0.001 160-170° (air bath temp)
 
Derivative Type: Dihydrochloride
Molecular Formula: C20H27Cl2N3S
Molecular Weight: 412.42
Percent Composition: C 58.24%, H 6.60%, Cl 17.19%, N 10.19%, S 7.77%
Properties: Hygroscopic needles, dec 228-230°.
 
Derivative Type: Dihydrochloride hemihydrate
Properties: Platelets from ethanol, mp 225-227°.
Melting point: mp 225-227°
 
Derivative Type: Dimaleate
Molecular Formula: C28H33N3O8S
Molecular Weight: 571.64
Percent Composition: C 58.83%, H 5.82%, N 7.35%, O 22.39%, S 5.61%
Properties: Crystals from water, mp 210°.
Melting point: mp 210°
 
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Phenothiazines.

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