Phenethylamine
Title: Phenethylamine
CAS Registry Number: 64-04-0
CAS Name: Benzeneethanamine
Additional Names: b-phenylethylamine; 1-amino-2-phenylethane; b-aminoethylbenzene; PEA
Molecular Formula: C8H11N
Molecular Weight: 121.18
Percent Composition: C 79.29%, H 9.15%, N 11.56%
Line Formula: C6H5CH2CH2NH2
Literature References: Endogenous amine related structurally and pharmacologically to amphetamine: P. Mantegazza, M. Riva, J. Pharm. Pharmacol. 15, 472 (1963). Present in oil of bitter almonds. Found in normal human urine (about 30 mg/liter). Prepn: Johnson, Guest, Am. Chem. J. 42, 346 (1909); Robinson, Snyder, Org. Synth. coll. vol. III, 720 (1955). Elevated levels in urine due to paranoid chronic schizophrenia: S. G. Potkin et al., Science 206, 470 (1979); due to stress: M. A. Paulos, R. E. Tessel, ibid. 215, 1127 (1982).
Properties: Liquid. Fishy odor. Absorbs CO2 from air. Does not solidify when cooled in an ice-salt mixture. Strong base. d425 0.9640; bp 194.5-195°. Sol in water. Freely sol in alc, ether.
Boiling point: bp 194.5-195°
Density: d425 0.9640
 
Derivative Type: Hydrochloride
Molecular Formula: C8H11N.HCl
Molecular Weight: 157.64
Percent Composition: C 60.95%, H 7.67%, N 8.89%, Cl 22.49%
Properties: Orthorhombic bipyramidal platelets from abs alcohol, mp 217°. Freely sol in water (100 parts H2O will dissolve 80 parts at 15°). Sol in alc. Insol in ether. LD50 s.c. in mice: 470 mg/kg (Mantegazza, Riva).
Melting point: mp 217°
Toxicity data: LD50 s.c. in mice: 470 mg/kg (Mantegazza, Riva)
 
CAUTION: Skin irritant and possible sensitizer.

Others monographs:
Lyapolate SodiumNPPBPapayaIsoflurane
Creslan®MatricarinTetroquinoneNinhydrin
XimoprofenMDAPolyvinyl AlcoholSarsaparilla
PhenolSunflower Seed OilThioguanosineAcetarsone
©2016 DrugLead US FDA&EMEA