Phenyramidol
Title: Phenyramidol
CAS Registry Number: 553-69-5
CAS Name: a-[(2-Pyridinylamino)methyl]benzenemethanol
Additional Names: 2-(b-hydroxyphenethylamino)pyridine; fenyramidol
Molecular Formula: C13H14N2O
Molecular Weight: 214.26
Percent Composition: C 72.87%, H 6.59%, N 13.07%, O 7.47%
Literature References: Prepn from 2-mandelamidopyridine or 2-aminopyridine: Gray et al., J. Am. Chem. Soc. 81, 4347, 4351 (1959).
Properties: Crystals from dil methanol, mp 82-85°. uv max (95% ethanol): 243, 303 nm (log e 4.24, 3.63). pKa 5.85.
Melting point: mp 82-85°
pKa: pKa 5.85
Absorption maximum: uv max (95% ethanol): 243, 303 nm (log e 4.24, 3.63)
 
Derivative Type: Hydrochloride
CAS Registry Number: 326-43-2
Manufacturers' Codes: IN-511; MJ-505; NSC-17777
Trademarks: Cabral (Solvay)
Molecular Formula: C13H14N2O.HCl
Molecular Weight: 250.72
Percent Composition: C 62.28%, H 6.03%, N 11.17%, O 6.38%, Cl 14.14%
Properties: Crystals from ethanol + ether, mp 140-142°. Soluble in water. Aq solns are slightly acid and stable in ampuls.
Melting point: mp 140-142°
 
Derivative Type: Methiodide
Molecular Formula: C13H14N2O.CH3I
Molecular Weight: 356.20
Percent Composition: C 47.21%, H 4.81%, N 7.86%, O 4.49%, I 35.63%
Properties: Crystals from ethanol + ether, mp 164-166°.
Melting point: mp 164-166°
 
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).

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