Phosalone
Title: Phosalone
CAS Registry Number: 2310-17-0
CAS Name: Phosphorodithioic acid S-[(6-chloro-2-oxo-3(2H)-benzoxazolyl)methyl] O,O-diethyl ester
Additional Names: phosphorodithioic acid, O,O-diethyl ester, S-ester with 6-chloro-3-(mercaptomethyl)-2-benzoxazolinone; 3-(O,O-diethyldithiophosphorylmethyl)-6-chlorobenzoxazolinone; 6-chloro-3-(O,O-diethyldithiophosphorylmethyl)benzoxazolone; S-(6-chloro-2-oxobenzoxazolin-3-yl)methyl diethyl phosphorothiolothionate
Manufacturers' Codes: RP-11974
Trademarks: Zolone (Rh>e-Poulenc)
Molecular Formula: C12H15ClNO4PS2
Molecular Weight: 367.81
Percent Composition: C 39.19%, H 4.11%, Cl 9.64%, N 3.81%, O 17.40%, P 8.42%, S 17.44%
Literature References: Organophosphorous pesticide; cholinesterase inhibitor. Prepn: GB 1005372 (1965 to Rhône-Poulenc). Toxicology, metabolism, insecticidal properties: D. L. Colinese, H. J. Terry, Chem. Ind. (London) 1968, 1507. Use as molluscicide: Cessac, FR 1453989 (1966 to Rhône-Poulenc).
Properties: Crystals, mp 47.5-48°. Sol in ketones, alcohols and most aromatic solvents. Practically insol in water and aliphatic hydrocarbons. LD50 in mice, female, male rats, guinea pigs (mg/kg): 180-205, 135-170, 120, 82-150 orally; female rats (mg/kg): 390 dermally (Colinese, Terry).
Melting point: mp 47.5-48°
Toxicity data: LD50 in mice, female, male rats, guinea pigs (mg/kg): 180-205, 135-170, 120, 82-150 orally; female rats (mg/kg): 390 dermally (Colinese, Terry)
Use: Insecticide, acaricide.

Others monographs:
Oil of RoseQuince SeedSuccinanilic AcidHementin
TyrothricinAmmoniacumCocaineDimemorfan
AmyleneCacao ShellSodium Selenate1,2-Dianilinoethane
Balsam Gurjun2-Ethyl-1-hexanolClobenzepamo-Phenylenediamine
©2016 DrugLead US FDA&EMEA