Phytic Acid
Title: Phytic Acid
CAS Registry Number: 83-86-3
CAS Name: myo-Inositol hexakis(dihydrogen phosphate)
Additional Names: inositolhexaphosphoric acid; 1,2,3,4,5,6-cyclohexanehexolphosphoric acid; cyclohexanehexyl hexaphosphate
Trademarks: Alkalovert (Klein)
Molecular Formula: C6H18O24P6
Molecular Weight: 660.04
Percent Composition: C 10.92%, H 2.75%, O 58.18%, P 28.16%
Line Formula: C6H6[OPO(OH)2]6
Literature References: Major phosphorus compound in plants; particularly abundant in oil seeds, legumes and cereal grains. Forms insoluble complexes with di- and trivalent cations. Prepn: S. Posternak, US 1313014 (1919 to Ciba); idem, Helv. Chim. Acta 4, 155 (1921); M. J. Thomas, US 2718523 (1955 to Staley Mfg.); D. S. Bolley et al., US 2732395 (1956 to Natl. Lead Co.); A. R. Baldwin et al., US 2815360 (1957 to Corn Prods. Ref.). HPLC determn in plants: E. Graf, F. R. Dintzis, Anal. Biochem. 119, 413 (1982); in foods and biological samples: B.E. Knuckles et al., J. Food Sci. 47, 1257 (1982). Review of effect of dietary phytate on zinc metabolism: Nutr. Rev. 41, 64-66 (1983); on mineral bioavailability: J. L. Kelsay, Am. J. Gastroenterol. 82, 983-986 (1987).
Properties: Syrupy, straw-colored liquid. Dec on heating. Acid reaction; the pH of a 10% aq soln has been reported as 0.86. Miscible with water, 95% alc, glycerol; sol in water contg alcohol-ether mixtures; very slightly sol in abs alc, methanol. Practically insol in anhydr ether, benzene, chloroform.
 
Derivative Type: Calcium iron salt
Properties: Obtained in the processing of corn. Grayish powder contg 20% Ca, 14% P, and 2% Fe. Sparingly sol in water, dil mineral acids.
 
Derivative Type: Calcium magnesium salt
CAS Registry Number: 3615-82-5
Additional Names: Phytin
Properties: White, odorless powder. Poor soly in water. Sol in dil acids.
 
Derivative Type: Sodium salt
CAS Registry Number: 7205-52-9
Additional Names: Sodium phytate
Trademarks: Phytat D.B. (Daniel-Brunet); Rencal (BMS)
Molecular Formula: C6H9Na9O24P6
Molecular Weight: 857.87
Percent Composition: C 8.40%, H 1.06%, Na 24.12%, O 44.76%, P 21.66%
Properties: Soluble in water with neutral reaction.
 
Use: Complexing agent for the removal of traces of heavy metal ions (also employed as the sodium salt). Starting material in manufacture of inositol. Fermentation nutrient.
Therap-Cat: Sodium salt as hypocalcemic.

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