Pipamazine
Title: Pipamazine
CAS Registry Number: 84-04-8
CAS Name: 1-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-4-piperidinecarboxamide
Additional Names: 1-[3-(2-chlorophenothiazin-10-yl)propyl]isonipecotamide; 10-[3-(4-carbamoylpiperidin-1-yl)propyl]-2-chlorophenothiazine; 2-chloro-10-[3-(4-carbamoylpiperidinyl)propyl]phenothiazine; 10-[3-(4-carbamoylpiperidino)propyl]-2-chlorophenothiazine
Manufacturers' Codes: SC-9387
Trademarks: Nausidol (SK & F); Mornidine (Searle)
Molecular Formula: C21H24ClN3OS
Molecular Weight: 401.95
Percent Composition: C 62.75%, H 6.02%, Cl 8.82%, N 10.45%, O 3.98%, S 7.98%
Literature References: Prepn: Cusic et al., US 2957870 (1960 to Searle).
Properties: Crystals from 2-propanol + petr ether, mp about 139°.
Melting point: mp about 139°
 
Derivative Type: Hydrochloride
Properties: Crystals, mp about 196-197° with formation of bubbles.
Melting point: mp about 196-197°
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic.

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