Pipamperone
Title: Pipamperone
CAS Registry Number: 1893-33-0
CAS Name: 1¢-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4¢-bipiperidine]-4¢-carboxamide
Additional Names: 1¢-[3-(p-fluorobenzoyl)propyl]-[1,4¢-bipiperidine]-4¢-carboxamide; 1-(p-fluorophenyl)-4-(4-piperidino-4-carbamoylpiperidino)-1-butanone; 1-[g-(4-fluorobenzoyl)propyl]-4-piperidinopiperidine-4-carboxamide; 4¢-fluoro-4-[N-[4-(N-piperidino)-4-carbamido]piperidino]butyrophenone; floropipamide
Manufacturers' Codes: R-3345
Molecular Formula: C21H30FN3O2
Molecular Weight: 375.48
Percent Composition: C 67.17%, H 8.05%, F 5.06%, N 11.19%, O 8.52%
Literature References: Prepn of the dihydrochloride by reaction of g-chloro-4-fluorobutyrophenone and 4-piperidinopiperidine-4-carboxamide: Janssen, BE 610830 (1962 to Janssen), C.A. 57, 13740b (1962).
 
Derivative Type: Dihydrochloride
CAS Registry Number: 2448-68-2
Trademarks: Dipiperon (Janssen); Piperonil (Lusofarmaco); Propitan (Eisai)
Molecular Formula: C21H30FN3O2.2HCl
Molecular Weight: 448.40
Percent Composition: C 56.25%, H 7.19%, F 4.24%, N 9.37%, O 7.14%, Cl 15.81%
Properties: Crystals, mp 124.5-126.0°.
Melting point: mp 124.5-126.0°
 
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Butyrophenones.

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