Poldine Methylsulfate
Title: Poldine Methylsulfate
CAS Registry Number: 545-80-2
CAS Name: 2-[[(Hydroxydiphenylacetyl)oxy]methyl]-1,1-dimethylpyrrolidinium methyl sulfate (salt)
Additional Names: 2-hydroxymethyl-1,1-dimethylpyrrolidinium methyl sulfate benzilate; 2-benziloyloxymethyl-1,1-dimethylpyrrolidinium methyl sulfate; (1-methyl-2-pyrrolidinyl)methyl benzilate methylmethosulfate
Manufacturers' Codes: IS-499; McN-R-726-47
Trademarks: Nacton (McNeil); Nactate
Molecular Formula: C22H29NO7S
Molecular Weight: 451.53
Percent Composition: C 58.52%, H 6.47%, N 3.10%, O 24.80%, S 7.10%
Literature References: Anticholinergic. Prepn: Doyle et al., J. Chem. Soc. 1958, 4458. Prepn of the base: Blicke, Lu, J. Am. Chem. Soc. 79, 29 (1955).
Properties: Needles from methyl ethyl ketone + ethanol + ether, mp 154-155°. Soluble in water.
Melting point: mp 154-155°
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.

Others monographs:
Calcium SulfidePropatyl NitrateGold Sodium ThiosulfateArborescin
Vanadium PentoxideFlunoxaprofenPropylidene ChlorideRacemethorphan
SyringaldehydePrednisoneAmmonium Cobaltous PhosphateIPBC
α1-SitosterolCadexomer IodineSesame OilCinnamyl Alcohol
©2016 DrugLead US FDA&EMEA