Pyrovalerone
Title: Pyrovalerone
CAS Registry Number: 3563-49-3
CAS Name: 1-(4-Methylphenyl)-2-(1-pyrrolidinyl)-1-pentanone
Additional Names: 4¢-methyl-2-(1-pyrrolidinyl)valerophenone; a-pyrrolidino-p-methylvalerophenone; 1-(1-pyrrolidinyl)butyl p-tolyl ketone; 1-(p-tolyl)-1-oxo-2-pyrrolidino-n-pentane; 1-(p-tolyl)-2-pyrrolidino-1-pentanone
Molecular Formula: C16H23NO
Molecular Weight: 245.36
Percent Composition: C 78.32%, H 9.45%, N 5.71%, O 6.52%
Literature References: Prepn: GB 927475 (1963 to Wander); GB 933507; E. Seeger, US 3314970 (1963, 1967 both to Thomae); Heffe, Helv. Chim. Acta 47, 1289 (1964). Pharmacology: Stille et al., Arzneim.-Forsch. 13, 871 (1963). Metabolism: Michaelis et al., J. Med. Chem. 13, 497 (1970).
Properties: bp0.08 104°.
Boiling point: bp0.08 104°
 
Derivative Type: Hydrochloride
CAS Registry Number: 1147-62-2
Manufacturers' Codes: F-1983
Trademarks: Centroton (Wander); Thymergix (Joulli)
Molecular Formula: C16H23NO.HCl
Molecular Weight: 281.82
Percent Composition: C 68.19%, H 8.58%, N 4.97%, O 5.68%, Cl 12.58%
Properties: Crystals from 2-butanone or from methanol + acetone + diethyl ether, mp 178°. LD50 orally in mice: 350 mg/kg (Stille).
Melting point: mp 178°
Toxicity data: LD50 orally in mice: 350 mg/kg (Stille)
 
NOTE: This is a controlled substance (stimulant): 21 CFR, 1308.15.
Therap-Cat: CNS stimulant.
Keywords: CNS Stimulant.

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