Racefemine
Title: Racefemine
CAS Registry Number: 22232-57-1
CAS Name: (aR)-rel-a-Methyl-N-[(1R)-1-methyl-2-phenoxyethyl]benzeneethanamine
Additional Names: threo-(±)-a-methyl-N-(1-methyl-2-phenoxyethyl)phenethylamine; dl-threo-a-methyl-N-(1-phenoxy-2-propyl)phenethylamine; dl-threo-N-(1-methyl-2-phenylethyl)-N-(2-phenoxy-1-methylethyl)amine
Molecular Formula: C18H23NO
Molecular Weight: 269.38
Percent Composition: C 80.26%, H 8.61%, N 5.20%, O 5.94%
Literature References: Uterine relaxant. Prepn: NL 6407309; J. Schmit, M. D. P. Brunaud, US 3437731 (1964, 1969 both to Clin-Byla). Clinical evaluation as utero-relaxant: P. Houlné, P. Hervé, Rev. Fr. Gynecol. Obstet. 62, 108 (1967); P. Dorangeon, ibid. 65, 385 (1970).
 
Derivative Type: Fumarate
CAS Registry Number: 10509-73-6
Manufacturers' Codes: 3697-CB
Trademarks: Dysmalgine
Molecular Formula: C18H23NO.C4H4O4
Molecular Weight: 385.45
Percent Composition: C 68.55%, H 7.06%, N 3.63%, O 20.75%
Properties: LD50 in mice (mg/kg): 420 orally; 240 s.c. (Houlnè).
Toxicity data: LD50 in mice (mg/kg): 420 orally; 240 s.c. (Houlnè)
 
NOTE: Has also been marketed as dextrofemine, the (+)-form.
Therap-Cat: Antispasmodic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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