Salicylamide O-Acetic Acid
Title: Salicylamide O-Acetic Acid
CAS Registry Number: 25395-22-6
CAS Name: [2-(Aminocarbonyl)phenoxy]acetic acid
Additional Names: o-(carbamylphenoxy)acetic acid; a-(2-carbamoylphenoxy)acetic acid
Molecular Formula: C9H9NO4
Molecular Weight: 195.17
Percent Composition: C 55.39%, H 4.65%, N 7.18%, O 32.79%
Literature References: Prepn: Merriman, J. Chem. Soc. 103, 1838 (1913); Tzofin, J. Gen. Chem. USSR 3, 17 (1933); Klosa, Arch. Pharm. 288, 389 (1955); Izumi et al., JP 56 874 (1956 to Yoshitomi). Pharmacokinetics and efficacy: D. Loew et al., Int. J. Clin. Pharmacol. Ther. Toxicol. 30, 509 (1992).
Properties: Crystals, mp 221°. Sol in aq alkali.
Melting point: mp 221°
 
Derivative Type: Sodium salt
CAS Registry Number: 3785-32-8
Trademarks: Salizell (amp.) (Byk Gulden)
Molecular Formula: C9H8NNaO4
Molecular Weight: 217.15
Percent Composition: C 49.78%, H 3.71%, N 6.45%, Na 10.59%, O 29.47%
Properties: Crystals, mp 212-215°.
Melting point: mp 212-215°
 
Derivative Type: Diethylamine salt
Trademarks: Akistin (Nycomed)
Molecular Formula: C13H22N2O4
Molecular Weight: 270.32
Percent Composition: C 57.76%, H 8.20%, N 10.36%, O 23.67%
 
Therap-Cat: Analgesic; anti-inflammatory; antipyretic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives; Antipyretic.

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