Secobarbital Sodium
Title: Secobarbital Sodium
CAS Registry Number: 309-43-3
CAS Name: 5-(1-Methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione monosodium salt
Additional Names: sodium 5-allyl-5-(1-methylbutyl)barbiturate; 5-allyl-5-(1-methylbutyl)barbituric acid sodium salt; 5-allyl-5-(1-methylbutyl)malonylurea sodium salt; meballymal sodium; quinalbarbitone sodium
Trademarks: Barbosec (Rowell); Immenoctal (Houd?; Pramil (HÝsle); Quinalspan (Pharmax); Sedutain (Key); Seconal Sodium (Lilly); Seotalnatrium (Lilly)
Molecular Formula: C12H17N2NaO3
Molecular Weight: 260.26
Percent Composition: C 55.38%, H 6.58%, N 10.76%, Na 8.83%, O 18.44%
Literature References: Prepn: US 1954429 (1934). Comprehensive description: I. Comer, Anal. Profiles Drug Subs. 1, 343-365 (1972). Toxicity data: E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972).
Properties: White, hygroscopic powder. Bitter taste. Very sol in water. Sol in alc. Practically insol in ether. Aq solns are alkaline to litmus. The soly in elixirs is increased by the presence of methenamine. LD50 orally in rats: 125 mg/kg (Schafer).
Toxicity data: LD50 orally in rats: 125 mg/kg (Schafer)
 
Derivative Type: Free acid
Molecular Formula: C12H18N2O3
Molecular Weight: 238.28
Percent Composition: C 60.49%, H 7.61%, N 11.76%, O 20.14%
Properties: mp 100°.
Melting point: mp 100°
 
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.12 and 1308.13.
Therap-Cat: Sedative; hypnotic.
Therap-Cat-Vet: Short-acting hypnotic; sedative. Pre-anesthetic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.

Others monographs:
OlsalazineDimethazanAdrenoglomerulotropinIsocrotonic Acid
VomitoxinFenpropathrinDehydroacetic AcidDidanosine
MeteloidineAldicarbAdlumineSodium Chlorite
PolidexideCeftiofurManebEthisterone
©2016 DrugLead US FDA&EMEA