Sodium Cacodylate
Title: Sodium Cacodylate
CAS Registry Number: 124-65-2
CAS Name: [(Dimethylarsino)oxy]sodium As-oxide
Additional Names: sodium dimethylarsonate
Trademarks: Arsecodile; Arsicodile; Arsycodile; Rad-e-cate (Vineland); Silvisar
Molecular Formula: C2H6AsNaO2
Molecular Weight: 159.98
Percent Composition: C 15.02%, H 3.78%, As 46.83%, Na 14.37%, O 20.00%
Literature References: An organic compd of arsenic yielding inorganic, trivalent arsenic in the body (is excreted partly unchanged, also yields dimethylarsine oxide). Prepd by the distillation of a mixture of arsenic trioxide and potassium acetate which yields Cadet's liquid, contg mostly dimethylarsine oxide. This is oxidized with mercuric oxide yielding crystals of cacodylic acid which is neutralized with Na2CO3 or NaOH: Cadet de Gassicourt, Mem. savants ├ętrangers 3, 633 (1760); Valeur, Gaillot, Compt. Rend. 185, 956 (1927). Use in treatment of psoriasis: S. I. Dawes, H. C. Jackson, J. Am. Med. Assoc. 48, 2020 (1903). Metabolism and excretion: A. Heffter, Arch. Exp. Pathol. Pharmakol. 46, 230 (1901). Use as herbicide: M. A. Sprague, US 3056663 (1962 to Ansul). Possible use in radiation dosimetry: H. S. Levinson, E. B. Garber, Nature 207, 751 (1965). Review of toxicology and human exposure: Toxicological Profile for Arsenic (PB2000-108021, 2000) 468 pp.
Derivative Type: Trihydrate
Properties: Crystals, granules. Slight odor. Liquefies in its water of hydration at about 60┬░. Becomes anhydr at 120┬░. Burns with a bluish flame, emitting a garlic-like odor. One gram dissolves in 0.5 ml water, 2.5 ml alcohol. pH about 8-9. Keep well closed.
Use: Herbicide.
Therap-Cat-Vet: Has been used in chronic eczema, anemia, as a tonic.

Others monographs:
ErgothioneineChromous OxalateHumic AcidsVerapamil
Mercumallylic AcidN-Nitrosodiethanolaminetert-Butyl HypochloriteMefexamide
Propyl BromideBeryllium BromideErdinSerpentaria
©2016 DrugLead US FDA&EMEA