Soterenol
Title: Soterenol
CAS Registry Number: 13642-52-9
CAS Name: N-[2-Hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide
Additional Names: 2¢-hydroxy-5¢-[1-hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide
Manufacturers' Codes: MJ-1992
Molecular Formula: C12H20N2O4S
Molecular Weight: 288.36
Percent Composition: C 49.98%, H 6.99%, N 9.71%, O 22.19%, S 11.12%
Literature References: b-Adrenergic agonist. Prepn: Larsen et al., J. Med. Chem. 10, 462 (1967). Pharmacological study: K. W. Dungan et al., J. Pharmacol. Exp. Ther. 164, 290 (1968).
 
Derivative Type: Monohydrochloride
CAS Registry Number: 14816-67-2
Molecular Formula: C12H20N2O4S.HCl
Molecular Weight: 324.82
Percent Composition: C 44.37%, H 6.52%, N 8.62%, O 19.70%, S 9.87%, Cl 10.91%
Properties: Crystals from methanol-isopropyl ether, mp 195.5-196.5° (dec). LD50 (7 day) in mice (mg/kg): 41 i.v.; 315 i.p.; 660 orally (Dungan).
Melting point: mp 195.5-196.5° (dec)
Toxicity data: LD50 (7 day) in mice (mg/kg): 41 i.v.; 315 i.p.; 660 orally (Dungan)
 
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.

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