Sulfaethidole
Title: Sulfaethidole
CAS Registry Number: 94-19-9
CAS Name: 4-Amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
Additional Names: N1-(5-ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide; 5-ethyl-2-sulfanilamido-1,3,4-thiadiazole; 2-(p-aminobenzenesulfonamido)-5-ethylthiadiazole; sulfaethylthiadiazole
Manufacturers' Codes: VK-55
Trademarks: Sul-Spantab (SK & F)
Molecular Formula: C10H12N4O2S2
Molecular Weight: 284.36
Percent Composition: C 42.24%, H 4.25%, N 19.70%, O 11.25%, S 22.55%
Literature References: The commercial prepn (Schering AG) is described in P.B. reports, no. 245, p 5, and no. 1361, p 73. Prepn: Wojahn, Wuckel, Arch. Pharm. 284, 53 (1951).
Properties: Crystals, mp 185.5-186.0°. One gram dissolves in 4000 ml water, in 40 g methanol, in 30 g ethanol, in 10 g acetone, in 1350 g ether, in 2800 g chloroform, in 20,000 g benzene. Faintly acid to litmus.
Melting point: mp 185.5-186.0°
 
Derivative Type: Sodium salt
Properties: pH of 20% soln: 7.5.
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antimicrobial.
Keywords: Antibacterial (Synthetic); Sulfonamides.

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