Sulfolane
Title: Sulfolane
CAS Registry Number: 126-33-0
CAS Name: Tetrahydrothiophene 1,1-dioxide
Additional Names: tetrahydrothiophene 1-dioxide; thiophan sulfone
Molecular Formula: C4H8O2S
Molecular Weight: 120.17
Percent Composition: C 39.98%, H 6.71%, O 26.63%, S 26.68%
Literature References: Prepn by catalytic hydrogenation of sulfolene oxides: Mahan, Fauske, US 2578565 (1951 to Phillips Petroleum); from butadiene and sulfur dioxide: Staaterman et al., Chem. Eng. Prog. 43, 148 (1947); Evans, Morris, US 2360859 (1944 to Shell). Toxicity study: H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 30, 470 (1962).
Properties: Liquid, d430 1.2606. mp 27.4-27.8°. bp760 285°. nD30 1.481. Viscosity at 30° = 10.34 cP. Flash pt, open cup: 350°F (176°C). At 30°, miscible with water, acetone, toluene; partially misc with octanes, olefins and naphthenes. LD50 orally in rats: 1.54 ml/kg (Smyth).
Melting point: mp 27.4-27.8°
Boiling point: bp760 285°
Flash point: Flash pt, open cup: 350°F (176°C)
Index of refraction: nD30 1.481
Density: d430 1.2606
Toxicity data: LD50 orally in rats: 1.54 ml/kg (Smyth)
Use: Selective solvent for liquid-vapor extractions.

Others monographs:
AllocholesterolCycloleucineIrsogladineGestonorone Caproate
CorycavidineVinyl ChlorideBlonanserinYeast
NorflurazonDexmedetomidineImibenconazoleHementin
RoxarsoneHeloniasIsothipendylBrotizolam
©2016 DrugLead US FDA&EMEA