Tetramethylurea
Title: Tetramethylurea
CAS Registry Number: 632-22-4
Additional Names: TMU
Trademarks: Temur
Molecular Formula: C5H12N2O
Molecular Weight: 116.16
Percent Composition: C 51.70%, H 10.41%, N 24.12%, O 13.77%
Line Formula: [(CH3)2N]2CO
Literature References: Prepn: Lawson, Croom, J. Org. Chem. 28, 232 (1963). Review of prepn, manuf, properties and use as solvent and as reagent: Lüttringhaus, Dirksen, Angew. Chem. Int. Ed. 3, 260 (1964).
Properties: Liquid with faint, pleasant odor, bp 176.5°, bp740 174.5°, bp12 63-64°. mp -1.2°. Flash pt ~75°C. d420 0.9687. nD25 1.4493. Dipole moment: 3.47 D in benzene. pKb 2. uv max: 217.5 nm (e 1940). Miscible with water and with all common organic solvents including petr ether. LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen).
Melting point: mp -1.2°
Boiling point: bp 176.5°; bp740 174.5°; bp12 63-64°
Flash point: Flash pt ~75°C
pKa: pKb 2
Index of refraction: nD25 1.4493
Absorption maximum: uv max: 217.5 nm (e 1940)
Density: d420 0.9687
Toxicity data: LD50 i.v. in rats: 1.1 g/kg (Lüttringhaus, Dirksen)
Use: As solvent and reagent.

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