Thiethylperazine
Title: Thiethylperazine
CAS Registry Number: 1420-55-9
CAS Name: 2-(Ethylthio)-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine
Additional Names: 3-ethylmercapto-10-(1¢-methylpiperazinyl-4¢-propyl)phenothiazine
Molecular Formula: C22H29N3S2
Molecular Weight: 399.62
Percent Composition: C 66.12%, H 7.31%, N 10.52%, S 16.05%
Literature References: Prepn: Bourquin et al., Helv. Chim. Acta 41, 1072 (1958).
Properties: Crystals from acetone, mp 62-64°. bp0.01 227°.
Melting point: mp 62-64°
Boiling point: bp0.01 227°
 
Derivative Type: Dimaleate
CAS Registry Number: 1179-69-7
Manufacturers' Codes: GS-95; NSC-130044
Trademarks: Torecan (Novartis); Toresten (Sankyo)
Molecular Formula: C22H29N3S2.2C4H4O4
Molecular Weight: 631.76
Percent Composition: C 57.03%, H 5.90%, N 6.65%, S 10.15%, O 20.26%
Properties: Crystals from methanol, dec 188-190°.
 
Derivative Type: Dihydrochloride
Molecular Formula: C22H29N3S2.2HCl
Molecular Weight: 472.54
Percent Composition: C 55.92%, H 6.61%, N 8.89%, S 13.57%, Cl 15.01%
Properties: Crystals from ethanol, mp 214-216°.
Melting point: mp 214-216°
 
Derivative Type: Dimalate
CAS Registry Number: 52239-63-1
Molecular Formula: C22H29N3S2.2C4H6O5
Molecular Weight: 667.79
Percent Composition: C 53.96%, H 6.19%, N 6.29%, S 9.60%, O 23.96%
Properties: Crystals from ethanol, mp 139°.
Melting point: mp 139°
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic.

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