Thiobarbital
Title: Thiobarbital
CAS Registry Number: 77-32-7
CAS Name: 5,5-Diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
Additional Names: 5,5-diethyl-2-thiobarbituric acid
Trademarks: Ibition (IBI)
Molecular Formula: C8H12N2O2S
Molecular Weight: 200.26
Percent Composition: C 47.98%, H 6.04%, N 13.99%, O 15.98%, S 16.01%
Literature References: Prepn: Fischer, Dilthey, Ann. 335, 350 (1904); Carrington, J. Chem. Soc. 1944, 124. Metabolism in man: Bush et al., J. Pharmacol. Exp. Ther. 134, 110 (1961).
Properties: Pale yellow needles from water, mp 180°. Sol in about 88 parts hot water, in ethanol, chloroform, ether, acetone, ammonia, alkalies. Sparingly sol in toluene. Practically insol in benzene.
Melting point: mp 180°
Therap-Cat: Antihyperthyroid.
Keywords: Antihyperthyroid.

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