Thioguanine
Title: Thioguanine
CAS Registry Number: 154-42-7
CAS Name: 2-Amino-1,7-dihydro-6H-purine-6-thione
Additional Names: 2-aminopurine-6-thiol
Trademarks: Lanvis (GSK); Tabloid (GSK)
Molecular Formula: C5H5N5S
Molecular Weight: 167.19
Percent Composition: C 35.92%, H 3.01%, N 41.89%, S 19.18%
Literature References: Prepn: Elion, Hitchings, J. Am. Chem. Soc. 77, 1676 (1955); Hitchings, Elion, US 2697709; US 2800473; US 2884667; Hitchings et al., US 3019224; US 3132144 (1954, 1957, 1959, 1962, and 1964, all to Burroughs Welcome).
Properties: Needles from water, mp >360°.
Melting point: mp >360°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Purine Analogs.

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