Thionaphthene-2-carboxylic Acid
Title: Thionaphthene-2-carboxylic Acid
CAS Registry Number: 6314-28-9
CAS Name: Benzo[b]thiophene-2-carboxylic acid
Additional Names: 2-benzothiophenecarboxylic acid; TNCA
Manufacturers' Codes: BL-5583
Molecular Formula: C9H6O2S
Molecular Weight: 178.21
Percent Composition: C 60.66%, H 3.39%, O 17.96%, S 17.99%
Literature References: Prepn: R. Weissgerber, O. Kruber, Ber. 53, 1551 (1920); eidem, DE 341837 (1921), Frdl. 13, 279 (1921); D. A. Shirley, M. D. Cameron, J. Am. Chem. Soc. 72, 2788 (1950); T. Higa, A. J. Krubsack, J. Org. Chem. 41, 3399 (1976). Use as anti-osteoporotic agent: C. M. Samour, J. A. Vida, US 4101668 (1978 to Bristol-Myers). Effect on total skeletal calcium in mice: J. C. Robin et al., J. Med. 11, 15 (1980). Mechanism of action study: J. C. Robin et al., Calcif. Tissue Int. 36, 194 (1984). Hypocalcemic effect: A. J. Johannesson et al., Endocrinology 117, 1508 (1985).
Properties: Prisms from alcohol or needles from water, mp 236° (Weissgerber). Also reported as crystals from benzene-ethyl acetate, mp 236-238° (Higa).
Melting point: mp 236° (Weissgerber); mp 236-238° (Higa)

Others monographs:
CapravirinePotassium Tetracyanomercurate(II)TolycaineIndenolol
ButriptylineOrnoprostilMethanethiolFisetin
Amaranth (Plant)Magnesium SalicylateUranyl ChlorideNitrogen Fluoride
Potassium PyrophosphateOlaquindoxCellocidinAmicoumacin A
©2016 DrugLead US FDA&EMEA