Tioxidazole
Title: Tioxidazole
CAS Registry Number: 61570-90-9
CAS Name: (6-Propoxy-2-benzothiazolyl)carbamic acid methyl ester
Additional Names: methyl 6-propoxy-2-benzothiazolylcarbamate
Manufacturers' Codes: Sch-21480
Trademarks: Tiox (Schering-Plough)
Molecular Formula: C12H14N2O3S
Molecular Weight: 266.32
Percent Composition: C 54.12%, H 5.30%, N 10.52%, O 18.02%, S 12.04%
Literature References: Structurally related to benzimidazole anthelmintics. Prepn and anthelmintic activity: M. M. Nafissi-Varchei, BE 840945; US 4006242 (1976, 1977 both to Schering). Physical data, activity against roundworms: E. Panitz et al., Experientia 34, 733 (1978). Anthelmintic effect against gastrointestinal parasites in naturally infected horses: J. H. Drudge et al., Am. J. Vet. Res. 41, 1383 (1980); E. T. Lyons et al., ibid. 42, 1048 (1981).
Properties: White odorless solid, mp 178-180°. Insoluble in water. Slightly sol in organic solvents.
Melting point: mp 178-180°
Therap-Cat-Vet: Anthelmintic for horses.

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