Tolpropamine
Title: Tolpropamine
CAS Registry Number: 5632-44-0
CAS Name: N,N,4-Trimethyl-g-phenylbenzenepropanamine
Additional Names: N,N-dimethyl-3-phenyl-3-p-tolylpropylamine; 3-dimethylamino-1-phenyl-1-p-tolylpropane
Molecular Formula: C18H23N
Molecular Weight: 253.38
Percent Composition: C 85.32%, H 9.15%, N 5.53%
Literature References: Prepn: Bockmühl, Stein, DE 925468 (1955 to Hoechst); Klosa, J. Prakt. Chem. 34, 312 (1966). Pharmacology: Sendrail, Gleizes, Therapie 15, 119 (1960).
 
Derivative Type: Hydrochloride
Trademarks: Pragman Gelee (Milanfarma)
Molecular Formula: C18H23N.HCl
Molecular Weight: 289.84
Percent Composition: C 74.59%, H 8.35%, N 4.83%, Cl 12.23%
Properties: mp 182-184°.
Melting point: mp 182-184°
 
Therap-Cat: Topical antihistaminic, antipruritic.
Keywords: Antihistaminic; Alkylamine Derivatives; Antipruritic.

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