1-Hexanol
Title: 1-Hexanol
CAS Registry Number: 111-27-3
Additional Names: n-Hexyl alcohol; amylcarbinol; pentylcarbinol; 1-hydroxyhexane
Molecular Formula: C6H14O
Molecular Weight: 102.17
Percent Composition: C 70.53%, H 13.81%, O 15.66%
Line Formula: CH3(CH2)4CH2OH
Literature References: Occurs as the acetate in seeds and fruits of Heracleum sphondylium L. and H. giganteum Fisch., Umbelliferae. Lab prepn by the action of butylmagnesium bromide on ethylene oxide: Dreger, Org. Synth. coll. vol. I, 306 (2nd ed., 1941). Reduction of 1,3-hexadienal with iron wire in the presence of nickel acetate: Zeisel, Neuwirth, Ann. 433, 127 (1923); cf. Baumgarten, Glatzel, Ber. 59, 2659 (1926); Kuhn, Hoffer, Ber. 63, 2165 (1930). Industrial prepn by reducing ethyl caproate with sodium in abs alcohol: Bouveault, Blanc, DE 164294 (1903). Toxicity study: H. F. Smyth et al., Arch. Ind. Hyg. Occup. Med. 4, 119 (1951).
Properties: Liquid. d425 0.8153; d435 0.8082. mp -51.6°. bp760 157°; bp400 138°; bp200 119.6°; bp100 102.8°; bp60 92°; bp40 83.7°; bp20 70.3°; bp10 58.2°; bp5 47.2°; bp1.0 24.4°. nD25 1.4162. Absorption spectrum: Massol, Faucon, Bull. Soc. Chim. [4] 11, 932. Flash pt, closed cup: 145°F (63°C). Slightly sol in water; miscible with alcohol, ether. LD50 orally in rats: 4.59 g/kg (Smyth).
Melting point: mp -51.6°
Boiling point: bp760 157°; bp400 138°; bp200 119.6°; bp100 102.8°; bp60 92°; bp40 83.7°; bp20 70.3°; bp10 58.2°; bp5 47.2°; bp1.0 24.4°
Flash point: Flash pt, closed cup: 145°F (63°C)
Index of refraction: nD25 1.4162
Density: d425 0.8153; d435 0.8082
Toxicity data: LD50 orally in rats: 4.59 g/kg (Smyth)
Use: Manuf antiseptics, hypnotics.

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