Cimigenol
Title: Cimigenol
CAS Registry Number: 3779-59-7
CAS Name: (3b,15a,16a,23R,24S)-16,23:16,24-Diepoxy-9,19-cyclolanostane-3,15,25-triol
Additional Names: cimicifugol
Molecular Formula: C30H48O5
Molecular Weight: 488.70
Percent Composition: C 73.73%, H 9.90%, O 16.37%
Literature References: From the resin of Cimicifuga racemosa Nutt. (Actaea racemosa L.), Ranunculaceae: Corsano, Spano, Atti Accad. Naz. Lincei Cl. Sci. Fis. Mat. Nat. Rend. 32, 674 (1962), C.A. 58, 11408e (1963). Structure: Corsano et al., Chem. Commun. 1965, 185; Corsano, Piancatelli, Ric. Sci. 37, 366 (1967); eidem, Gazz. Chim. Ital. 99, 1140 (1969). Identity with cimicifugol: J. Pharm. Soc. Jpn. 87, 1569 (1967).
Properties: Needles from methanol, mp 227.5-228.5°. [a]D +38° (c = 0.86 in chloroform).
Melting point: mp 227.5-228.5°
Optical Rotation: [a]D +38° (c = 0.86 in chloroform)
 
Derivative Type: Diacetate
Molecular Formula: C34H52O7
Molecular Weight: 572.77
Percent Composition: C 71.30%, H 9.15%, O 19.55%
Properties: Needles from hexane, mp 202-204°. [a]D +46.3° (c = 1.07 in chloroform).
Melting point: mp 202-204°
Optical Rotation: [a]D +46.3° (c = 1.07 in chloroform)
 
Derivative Type: Triacetate
Molecular Formula: C36H54O8
Molecular Weight: 614.81
Percent Composition: C 70.33%, H 8.85%, O 20.82%
Properties: Needles from hexane, mp 149.5-150.5°. [a]D +25.4° (chloroform).
Melting point: mp 149.5-150.5°
Optical Rotation: [a]D +25.4° (chloroform)

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