Cinchomeronic Acid
Title: Cinchomeronic Acid
CAS Registry Number: 490-11-9
CAS Name: 3,4-Pyridinedicarboxylic acid
Molecular Formula: C7H5NO4
Molecular Weight: 167.12
Percent Composition: C 50.31%, H 3.02%, N 8.38%, O 38.29%
Literature References: Prepd in 42% yield by boiling quinine with nitric and fuming nitric acid: Ternájgo, Monatsh. Chem. 21, 448 (1900); cf. Kirpal, ibid. 23, 248 (1902); Kaas, ibid. 252; by selenium dioxide oxidation of isoquinoline: Mueller, US 2436660 (1948 to Allied Chem.).
Properties: Crystals from acidulated water, mp 256°. On heating, a small portion sublimes without decompn. Strong acid. Sparingly sol in hot alc, ether, benzene. Insol in chloroform.
Melting point: mp 256°
 
Derivative Type: Disodium salt dihydrate
Molecular Formula: C7H3NNa2O4.2H2O
Molecular Weight: 247.11
Percent Composition: C 34.02%, H 2.86%, N 5.67%, Na 18.61%, O 38.85%
Properties: Plates, moderately sol in water, alcohol.
 
Derivative Type: Dimethyl ester
Molecular Formula: C9H9NO4
Molecular Weight: 195.17
Percent Composition: C 55.39%, H 4.65%, N 7.18%, O 32.79%
Properties: Crystals, mp 141°.
Melting point: mp 141°

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