Title:  Diethylpropion 
CAS Registry Number:  90-84-6 
CAS Name:  2-(Diethylamino)-1-phenyl-1-propanone 
Additional Names:  2-diethylaminopropiophenone;  a-benzoyltriethylamine;  amfepramone 
Molecular Formula:  C13H19NO 
Molecular Weight:  205.30 
Percent Composition:  C 76.05%, H 9.33%, N 6.82%, O 7.79% 
Literature References:  Prepn:  Hyde et al., J. Am. Chem. Soc. 50, 2287 (1928); Schutte, US 3001910 (1961 to Temmler-Werke).  Pharmacology:  Cahen et al., Therapie 17, 373-412 (1962).  Clinical trial in obesity:  R. Abramson et al., J. Clin. Psychiatry 41, 234 (1980). 
  
Derivative Type:  Hydrochloride  
CAS Registry Number:  134-80-5 
Trademarks:  Anorex (Crinex);  Dobesin (Abigo);  Moderatan (Theranol);  Prefamone (Dexo);  Regenon (Temmler);  Tenuate (Aventis);  Tepanil (3M Pharma) 
Molecular Formula:  C13H19NO.HCl 
Molecular Weight:  241.76 
Percent Composition:  C 64.58%, H 8.34%, N 5.79%, O 6.62%, Cl 14.66% 
Properties:  Crystals, dec 168°. 
  
NOTE:  This is a controlled substance (stimulant):  21 CFR, 1308.14. 
Therap-Cat:  Anorexic. 
Keywords:  Anorexic; CNS Stimulant.   |