Title: Fenozolone
CAS Registry Number: 15302-16-6
CAS Name: 2-(Ethylamino)-5-phenyl-4(5H)-oxazolone
Additional Names: 2-ethylamino-4-oxo-5-phenyl-D2-oxazoline; 5-phenyl-2-(ethylimino)-4-oxazolidone; 5-phenyl-2-ethylamino-4-oxazolinone
Manufacturers' Codes: LD-3394
Trademarks: Ordinator (Dausse)
Molecular Formula: C11H12N2O2
Molecular Weight: 204.23
Percent Composition: C 64.69%, H 5.92%, N 13.72%, O 15.67%
Literature References: Prepn: Najer, Giudicelli, Bull. Soc. Chim. Fr. 1961, 1231; BE 613985 and DE 1297108 (1962, 1969 both to Dausse), C.A. 57, 13761a (1962); 71, 70586k (1969). Exists predominantly in the tautomeric ethylaminooxazolinone form: Najer et al., Compt. Rend. 254, 2173 (1962). Activity studies: Giudicelli et al., ibid. 2862.
Properties: Crystals from benzene, mp 148°. Stable in alkaline, unstable in acid soln. uv max (alcohol): 221 nm (log e 4.42). LD50 in white mice (g/kg): 0.425 orally; 0.175 i.p. (BE 613985).
Melting point: mp 148°
Absorption maximum: uv max (alcohol): 221 nm (log e 4.42)
Toxicity data: LD50 in white mice (g/kg): 0.425 orally; 0.175 i.p. (BE 613985)
Therap-Cat: CNS stimulant.
Keywords: CNS Stimulant.

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