Iopronic Acid
Title: Iopronic Acid
CAS Registry Number: 41473-08-9
CAS Name: 2-[[2-[3-(Acetylamino)-2,4,6-triiodophenoxy]ethoxy]methyl]butanoic acid
Additional Names: (±)-2-[[2-(3-acetamido-2,4,6-triiodophenoxy)ethoxy]methyl]butyric acid; 3-[2-(3-acetylamino-2,4,6-triiodophenoxy)ethoxy]-2-ethylpropionic acid
Manufacturers' Codes: B-11420; SQ-21983
Trademarks: Bilimiro (Bracco); Bilimiron (Bracco); Oravue (BMS); Videobil (Bracco)
Molecular Formula: C15H18I3NO5
Molecular Weight: 673.02
Percent Composition: C 26.77%, H 2.70%, I 56.57%, N 2.08%, O 11.89%
Literature References: Oral cholecystographic agent. Prepn: E. Felder, D. Pitre, DE 2128902; eidem, US 3842124 (1972, 1974 both to Bracco); E. Felder et al., Farmaco Ed. Sci. 31, 349 (1976). Pharmacology, toxicology: P. Tirone, G. Rosati, Farmaco Ed. Prat. 31, 397, 437 (1976). Series of articles on metabolism: ibid. 516-546; 755. Intestinal absorption: J. R. Amberg et al., Invest. Radiol. 15, S136 (1980). Effect on bile flow and composition: J. L. Barnhart et al., ibid. S124. Toxicity: P. Tirone, G. Rosati, Farmaco Ed. Prat. 31, 397 (1976).
Properties: Crystals from 50% ethanol, mp 130°. LD50 in mice, rats, dogs (mg/kg): 1950, 5650, >3000 orally; 1090, 1000, 835 i.v. (Tirone).
Melting point: mp 130°
Toxicity data: LD50 in mice, rats, dogs (mg/kg): 1950, 5650, >3000 orally; 1090, 1000, 835 i.v. (Tirone)
Therap-Cat: Diagnostic aid (radiopaque medium¾cholecystographic).
Keywords: Diagnostic Aid (Radiopaque Medium).

Others monographs:
MetaldehydeButamisoleNitrogen PentoxideSophorabioside
PhenylethanolamineXylenolδ -CaroteneCinnarizine
PyridazineFlutriafolCupric OxideIfosfamide
Tantalum PentafluorideDiamondEnallylpropymalLoratadine
©2014 DrugLead US FDA&EMEA