Bunaftine
Title: Bunaftine
CAS Registry Number: 32421-46-8
CAS Name: N-Butyl-N-[2-(diethylamino)ethyl]-1-naphthalenecarboxamide
Additional Names: N-butyl-N-[2-(diethylamino)ethyl]-1-naphthamide; bunaphtide; bunaphtine
Molecular Formula: C21H30N2O
Molecular Weight: 326.48
Percent Composition: C 77.26%, H 9.26%, N 8.58%, O 4.90%
Literature References: Prepn: M. Giannini, DE 2099894 (1971 to Malesci), C.A. 75, 20222a (1971); M. Giannini et al., Farmaco Ed. Sci. 28, 429 (1973). Pharmacology: A. Ferroni, G. Monticelli, Pharmacol. Res. Commun. 5, 151 (1973). Clinical pharmacokinetics: B. Flouvat et al., Therapie 37, 143 (1982).
Properties: bp0.1 178°. LD50 i.p. in mice: 122 mg/kg (Giannini et al.).
Boiling point: bp0.1 178°
Toxicity data: LD50 i.p. in mice: 122 mg/kg (Giannini et al.)
 
Derivative Type: Citrate
CAS Registry Number: 94157-87-6
Trademarks: Meregon (Malesci)
Molecular Formula: C21H30N2O.C6H8O7
Molecular Weight: 518.60
Percent Composition: C 62.53%, H 7.39%, N 5.40%, O 24.68%
 
Therap-Cat: Antiarrhythmic (class III).
Keywords: Antiarrhythmic.

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