Cyclopentolate
Title: Cyclopentolate
CAS Registry Number: 512-15-2
CAS Name: a-(1-Hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester
Additional Names: 1-hydroxy-a-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester; 2-dimethylaminoethyl 1-hydroxy-a-phenylcyclopentaneacetate; b-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate; 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid b-(dimethylamino)ethyl ester
Molecular Formula: C17H25NO3
Molecular Weight: 291.39
Percent Composition: C 70.07%, H 8.65%, N 4.81%, O 16.47%
Literature References: Ophthalmic anticholinergic. Prepn: Treves, US 2554511 (1951 to Schieffelin).
 
Derivative Type: Hydrochloride
CAS Registry Number: 5870-29-1
Trademarks: Ak-Pentolate (Akorn); Alnide (Cusi); Mydplegic (Cooper); Cyclogyl (Alcon); Mydrilate (Boehringer, Ing.); Zyklolat (Mann)
Molecular Formula: C17H25NO3.HCl
Molecular Weight: 327.85
Percent Composition: C 62.28%, H 7.99%, N 4.27%, O 14.64%, Cl 10.81%
Properties: Crystals from ethyl acetate, mp 137-141°. pH of 1% aq soln: 5.0-5.4. Freely sol in water, alcohol. Practically insol in ether.
Melting point: mp 137-141°
 
Therap-Cat: Mydriatic.
Keywords: Mydriatic; Antimuscarinic.

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