Deanol
Title: Deanol
CAS Registry Number: 108-01-0
CAS Name: 2-(Dimethylamino)ethanol
Additional Names: b-dimethylaminoethyl alcohol; N,N-dimethyl-2-hydroxyethylamine
Molecular Formula: C4H11NO
Molecular Weight: 89.14
Percent Composition: C 53.90%, H 12.44%, N 15.71%, O 17.95%
Line Formula: (CH3)2NCH2CH2OH
Literature References: Prepd from equimolar amounts of ethylene oxide and dimethylamine: Knorr, Ber. 37, 3508 (1904); Hanhart, Ingold, J. Chem. Soc. 1927, 1012. Clinical trial in hyperkinetic children: N. Coleman et al., Psychosomatics 17, 68 (1976); in involuntary movement disorders: D. E. Casey, Dis. Nerv. Syst. 38, 7 (1977).
Properties: Liquid. d420 0.8866. bp758 135°. nD20 1.43. Miscible with water, alcohol, ether.
Boiling point: bp758 135°
Index of refraction: nD20 1.43
Density: d420 0.8866
 
Derivative Type: Aceglumate
CAS Registry Number: 3342-61-8
Trademarks: Clérégil (Merck-Cl¢enot); Risatarun (Ravensberg)
Molecular Formula: C4H11NO.C7H11NO5
Molecular Weight: 278.30
Percent Composition: C 47.47%, H 7.97%, N 10.07%, O 34.49%
Literature References: Prepn: FR M2487 (1964 to Interco Fribourg), C.A. 61, 12085c (1964).
Properties: Sol in water.
 
Derivative Type: Acetamidobenzoate
CAS Registry Number: 3635-74-3
Trademarks: Deaner (3M Pharma); Pabenol (Gentili)
Molecular Formula: C4H11NO.C9H9NO3
Molecular Weight: 268.31
Percent Composition: C 58.19%, H 7.51%, N 10.44%, O 23.85%
Literature References: Prepn: GB 879259 (1957 to Riker Labs); A. Lasslo et al., J. Am. Pharm. Assoc. Sci. Ed. 48, 345 (1959).
Properties: Crystals from absolute ethanol + ethyl acetate, mp 159-161.5°. Sol in water.
Melting point: mp 159-161.5°
 
Derivative Type: Bitartrate
CAS Registry Number: 5988-51-2
Trademarks: Liparon (Finadiet)
Molecular Formula: C4H11NO.C4H6O6
Molecular Weight: 239.22
Percent Composition: C 40.17%, H 7.16%, N 5.86%, O 46.82%
Properties: Crystals, sol in water.
 
Derivative Type: Hemisuccinate
Trademarks: Tonibral (Bouchara); Rischiaril (Piam)
Molecular Formula: C4H11NO.C4H6O4
Molecular Weight: 207.22
Percent Composition: C 46.37%, H 8.27%, N 6.76%, O 38.60%
Properties: White, hygroscopic crystalline powder. Very soluble in water, ethanol; sparingly sol in chloroform, benzene.
 
Therap-Cat: CNS stimulant.
Keywords: CNS Stimulant.

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