Flumequine
Title: Flumequine
CAS Registry Number: 42835-25-6
CAS Name: 9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid
Manufacturers' Codes: R-802
Trademarks: Apurone (3M Pharma); Fantacin (Kyowa Hakko)
Molecular Formula: C14H12FNO3
Molecular Weight: 261.25
Percent Composition: C 64.36%, H 4.63%, F 7.27%, N 5.36%, O 18.37%
Literature References: Fluorinated quinolone antibacterial. Prepn: J. F. Gerster, DE 2264163; idem, US 3896131 (1973, 1975 both to Riker). In vitro study: G. Stilwell et al., Antimicrob. Agents Chemother. 7, 483 (1975). Bioevaluation: S. R. Rohlfing et al., J. Antimicrob. Chemother. 3, 615 (1977). Activity vs E. coli: D. Greenwood, Antimicrob. Agents Chemother. 13, 479 (1978).
Properties: White microcrystalline powder, mp 253-255°. Sol in alkaline solns and alcohol. Insol in water.
Melting point: mp 253-255°
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs.

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