Heptaminol
Title: Heptaminol
CAS Registry Number: 372-66-7
CAS Name: 6-Amino-2-methyl-2-heptanol
Additional Names: 2-methyl-6-amino-2-heptanol; 6-methyl-2-amino-6-heptanol
Molecular Formula: C8H19NO
Molecular Weight: 145.24
Percent Composition: C 66.16%, H 13.19%, N 9.64%, O 11.02%
Literature References: Prepn: H. T. F. Givens, R. M. Herbst, US 2457656 (1948 to Bilhuber); of hydrochloride: J. Doeuvre, J. Poizat, Compt. Rend. 224, 286 (1947). Pharmacokinetics and metabolism: F. Chanoine et al., Arzneim.-Forsch. 31, 1430 (1981). HPLC determn in biological fluids: R. R. Brodie et al., J. Chromatogr. 274, 179 (1983). Clinical trial in hypotension: D. Milon et al., Fundam. Clin. Pharmacol. 4, 695 (1990). Review of mode of action: B. Pourrias Ann. Pharm. Fr. 49, 127-138 (1991).
Properties: Colorless liquid, bp7 92-93°.
Boiling point: bp7 92-93°
 
Derivative Type: Hydrochloride
CAS Registry Number: 543-15-7
Manufacturers' Codes: RP-2831
Trademarks: Cortensor; Eoden (Woelm); Hept-a-myl (Delalande); Heptylon (Delalande)
Molecular Formula: C8H19NO.HCl
Molecular Weight: 181.70
Percent Composition: C 52.88%, H 11.09%, N 7.71%, O 8.81%, Cl 19.51%
Properties: Crystals, mp 150°. Freely sol in water. Sol in alcohol. Practically insol in acetone, benzene, ether. pH of 2% aq soln: 4.5-5.5.
Melting point: mp 150°
 
Derivative Type: 5¢-Adenylate
CAS Registry Number: 57249-13-5
Trademarks: Ampecyclal (Sarget)
 
Therap-Cat: Antihypotensive.
Keywords: Cardiotonic.

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