Medrysone
Title: Medrysone
CAS Registry Number: 2668-66-8
CAS Name: (6a,11b)-11-Hydroxy-6-methylpregn-4-ene-3,20-dione
Additional Names: 11b-hydroxy-6a-methylprogesterone; 6a-methyl-11b-hydroxyprogesterone; hydroxymesterone
Manufacturers' Codes: U-8471
Trademarks: HMS (Allergan)
Molecular Formula: C22H32O3
Molecular Weight: 344.49
Percent Composition: C 76.70%, H 9.36%, O 13.93%
Literature References: Prepn and use as an intermediate: Sebek et al., Spero, Thompson, US 2864837 and US 2968655 (1958 and 1961, both to Upjohn). In treatment of ocular inflammation: Bedrossian, Arch. Ophthalmol. 81, 184 (1969).
Properties: Crystals, mp 155-158°. [a]D +189° (in chloroform).
Melting point: mp 155-158°
Optical Rotation: [a]D +189° (in chloroform)
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.

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