Metescufylline
Title: Metescufylline
CAS Registry Number: 15518-82-8
CAS Name: [(7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-6-yl)oxy]acetic acid compd with 7-[2-(diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1)
Additional Names: 7-[2-(diethylamino)ethyl]theophylline compd with [(7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-6-yl)oxy]acetic acid (1:1); etamiphylline methesculetol; methescufylline; theophylline methesculetol
Trademarks: Veinartan; Venarterin (B.O.I.)
Molecular Formula: C25H31N5O8
Molecular Weight: 529.54
Percent Composition: C 56.70%, H 5.90%, N 13.23%, O 24.17%
Literature References: Prepn: P. Chabrier et al., FR M1234 (1962 to Lab. Dausse), C.A. 57, 16769f (1962).
Properties: Crystals, mp 124°. Slightly sol in cold water; freely sol in hot water. Practically insoluble in acetone. LD50 i.v. in mice: 260 mg/kg (Chabrier).
Melting point: mp 124°
Toxicity data: LD50 i.v. in mice: 260 mg/kg (Chabrier)
Therap-Cat: Capillary protectant.
Keywords: Vasoprotectant.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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