Moxaverine
Title: Moxaverine
CAS Registry Number: 10539-19-2
CAS Name: 3-Ethyl-6,7-dimethoxy-1-(phenylmethyl)isoquinoline
Additional Names: 1-benzyl-3-ethyl-6,7-dimethoxyisoquinoline
Molecular Formula: C20H21NO2
Molecular Weight: 307.39
Percent Composition: C 78.15%, H 6.89%, N 4.56%, O 10.41%
Literature References: Prepn of hydrochloride: FR 1362765 (1964 to Orgamol, SA), C.A. 62, 536f (1965). Physical properties and solution stability: E. Pawelczyk, M. Zajac, Diss. Pharm. Pharmacol. 24, 5 (1972). HPLC determn in pharmaceutical formulations: E. H. Girgis, J. Pharm. Sci. 82, 503 (1993).
Properties: Crystals, mp 71-72.5°. uv max (0.1 M H2SO4): 253 nm (A1cm1% 2164).
Melting point: mp 71-72.5°
Absorption maximum: uv max (0.1 M H2SO4): 253 nm (A1cm1% 2164)
 
Derivative Type: Hydrochloride
CAS Registry Number: 1163-37-7
Trademarks: Eupaverin (Merck KGaA); Eupaverina (Bracco); Kollateral (Ursapharm)
Molecular Formula: C20H21NO2.HCl
Molecular Weight: 343.85
Percent Composition: C 69.86%, H 6.45%, N 4.07%, O 9.31%, Cl 10.31%
Properties: Crystals from ethanol, mp 208-210° (dec). Sol in hot water, hot alc, and many other organic solvents; very sparingly sol in cold water.
Melting point: mp 208-210° (dec)
 
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.

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