Neurine
Title: Neurine
CAS Registry Number: 463-88-7
CAS Name: N,N,N-Trimethylethenaminium hydroxide
Additional Names: trimethylvinylammonium hydroxide
Molecular Formula: C5H13NO
Molecular Weight: 103.16
Percent Composition: C 58.21%, H 12.70%, N 13.58%, O 15.51%
Literature References: Found in egg yolk, brain, bile, in cadavers. Formed during putrefaction by dehydration of choline: Hofmann, Compt. Rend. 47, 559 (1858); Renshaw, Ware, J. Am. Chem. Soc. 47, 2992 (1925). Prepn: Meyer, Hopff, Ber. 54, 2277 (1921); from aq trimethylamine and acetylene: Gardner et al., J. Chem. Soc. 1949, 789. Separation and identification in biological fluids: E. Merlevede et al., Arch. Int. Pharmacodyn. 122, 474 (1959). Stereoelectronic config: Intern. Kongr. Entomol. Verhandl., 11th, Vienna, 1960, No. 3, pp 87-93, C.A. 57, 7749b (1962). Toxicity study: Hunt, J. Pharmacol. Exp. Ther. 28, 267 (1926).
Properties: Syrupy liq. Fishy odor. Poisonous! Forms a crystalline trihydrate. Alkaline reaction. Readily absorbs CO2 from the air. Sol in water, alcohol. Dec readily, forming trimethylamine. Forms an HCl salt. LD s.c. in mice: 46 mg/kg (Hunt).
Toxicity data: LD s.c. in mice: 46 mg/kg (Hunt)

Others monographs:
SuccinylsulfathiazoleLaudanosineDimethomorphCadralazine
o-AminoazotoluenePyrithiamineFerric Phosphatep-Cresyl Phenylacetate
DSIPPropyphenazoneCobaltous HydroxidePenicillin V Hydrabamine
DihydrothebaineTetraphosphorus TrisulfideDipropalinGangliosides
©2016 DrugLead US FDA&EMEA