Ornoprostil
Title: Ornoprostil
CAS Registry Number: 70667-26-4
CAS Name: (1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-e,5-dioxocyclopentaneheptanoic acid
Additional Names: (11a,13E,15S,17S)-11,15-dihydroxy-17,20-dimethyl-6,9-dioxoprost-13-en-1-oic acid methyl ester; 17S,20-dimethyl-6-oxoprostaglandin E1 methyl ester; 6-oxo-17S,20-dimethyl-PGE1 methyl ester; ronoprost
Manufacturers' Codes: ONO-1308; OU-1308
Trademarks: Alloca (Pharmacia & Upjohn); Ronok (Ono)
Molecular Formula: C23H38O6
Molecular Weight: 410.54
Percent Composition: C 67.29%, H 9.33%, O 23.38%
Literature References: Analog of prostaglandin E1, q.v. Prepn: M. Hayashi et al., DE 2840032; eidem, US 4278688 (1979, 1981 both to Ono). Effect on gastric mucosal lesions in rats: H. Kuwata et al., Nippon Shokakibyo Gakkai Zasshi 82, 1858 (1985), C.A. 104, 15709c (1986); eidem, Curr. Clin. Pract. Ser. 36, 243 (1986); on experimental esophagitis: S. Inoue et al., Gendai Iyro 19, 1348 (1987), C.A. 107, 626m (1987).
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Prostaglandin/Prostaglandin Analog.

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