Phenyl Aminosalicylate
Title: Phenyl Aminosalicylate
CAS Registry Number: 133-11-9
CAS Name: 4-Amino-2-hydroxybenzoic acid phenyl ester
Additional Names: p-aminosalicylic acid phenyl ester; phenyl p-aminosalicylic acid; p-aminosalol; fenamisal
Trademarks: Phenyl PAS; Pheny-PAS-Tebamin (Purdue Frederick); Tebamin; Tebanyl
Molecular Formula: C13H11NO3
Molecular Weight: 229.23
Percent Composition: C 68.11%, H 4.84%, N 6.11%, O 20.94%
Literature References: Description of properties: Meyer, Antibiot. Annu. 1957-1958, 614. Prepd by Raney nickel reduction of the corresp nitro ester in ethyl acetate: Friere, US 2604488 (1952 to Rhône-Poulenc).
Properties: Crystals from isopropanol, mp 153°. Soly in water: 0.7 mg/100 ml; in serum: 12 mg/100 ml. One gram of phenyl PAS is equivalent to 0.67 g PAS.
Melting point: mp 153°
Therap-Cat: Antibacterial (tuberculostatic).
Keywords: Antibacterial (Tuberculostatic).

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