Physodic Acid
Title: Physodic Acid
CAS Registry Number: 84-24-2
CAS Name: 3,8-Dihydroxy-11-oxo-1-(2-oxoheptyl)-6-pentyl-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid
Additional Names: 4,4¢,6¢-trihydroxy-6-(2-oxoheptyl)-2¢-pentyl-2,3¢-oxydibenzoic acid-e-lactone; physodalin
Molecular Formula: C26H30O8
Molecular Weight: 470.51
Percent Composition: C 66.37%, H 6.43%, O 27.20%
Literature References: From the lichens Parmelia physodes (L.) Ach.: Hesse, Ber. 30, 1983 (1897); Klosa, Pharm. Ind. 15, 46 (1953); and Cetraria ciliaris Ach.: Culberson, Science 143, 255 (1964). Structure: Asahina, Nogami, Ber. 67, 805 (1934); 68, 77 (1935).
Properties: Needles from methanol, mp 205°. uv max (95% ethanol): 256 nm (log e 4.2). Sol in ether, acetone, hot methanol; somewhat sol in cold ethanol, methanol, hot chloroform; practically insol in benzene, petr ether, carbon disulfide.
Melting point: mp 205°
Absorption maximum: uv max (95% ethanol): 256 nm (log e 4.2)
 
Derivative Type: Diacetate
Molecular Formula: C30H34O10
Molecular Weight: 554.58
Percent Composition: C 64.97%, H 6.18%, O 28.85%
Properties: Plates from acetone + carbon disulfide, mp 153-155.5°.
Melting point: mp 153-155.5°
 
Derivative Type: Methyl ester
Molecular Formula: C27H32O8
Molecular Weight: 484.54
Percent Composition: C 66.93%, H 6.66%, O 26.42%
Properties: Prisms from 80% alcohol, mp 156-157°.
Melting point: mp 156-157°

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