Ponceau SX
Title: Ponceau SX
CAS Registry Number: 4548-53-2
CAS Name: 3-[(2,4-Dimethyl-5-sulfophenyl)azo]-4-hydroxy-1-naphthalenesulfonic acid disodium salt
Additional Names: FD & C Red No. 4; C.I. Food Red 1; C.I. 14700
Molecular Formula: C18H14N2Na2O7S2
Molecular Weight: 480.42
Percent Composition: C 45.00%, H 2.94%, N 5.83%, Na 9.57%, O 23.31%, S 13.35%
Literature References: Azo dye. Prepn: E. Nölting, O. Kohn, Ber. 19, 137 (1886). Metabolism: J. L. Radomski, T. J. Mellinger, J. Pharmacol. Exp. Ther. 136, 259 (1962). Toxicity studies: F. C. Lu, A. Lavalle, Can. Pharm. J. 97, 30 (1964); K. J. Davis et al., Toxicol. Appl. Pharmacol. 8, 306 (1966). Determn in maraschino cherries: R. E. Draper, J. Assoc. Off. Anal. Chem. 56, 703 (1973); HPLC determn in lipstick: L. Gagliardi et al., J. Chromatogr. 394, 345 (1987). Review: IARC Monographs 8, 207-214 (1975). See also: Colour Index vol. 4 (3rd ed., 1971) p 4068.
Properties: Red crystals. Absorption max (0.02 N CH3COONH4): 500 nm. Sol in water; slightly sol in ethanol. Insol in vegetable oils. Deep red soln in conc H2SO4, changing to red ppt on dilution. Orange soln in conc HNO3, turning yellow. LD50 orally in rats: >2 g/kg (Lu, Lavalle).
Absorption maximum: Absorption max (0.02 N CH3COONH4): 500 nm
Toxicity data: LD50 orally in rats: >2 g/kg (Lu, Lavalle)
Use: Dye in externally applied drugs, cosmetics; food colorant in maraschino cherries.

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