Prilocaine
Title: Prilocaine
CAS Registry Number: 721-50-6
CAS Name: N-(2-Methylphenyl)-2-(propylamino)propanamide
Additional Names: 2-(propylamino)-o-propionotoluidide; N-(a-propylaminopropionyl)-o-toluidine; a-propylamino-2-methylpropionanilide; propitocaine
Molecular Formula: C13H20N2O
Molecular Weight: 220.31
Percent Composition: C 70.87%, H 9.15%, N 12.72%, O 7.26%
Literature References: Prepn: N. Löfgren, C. Tegner, Acta Chem. Scand. 14, 486 (1960); GB 839943; N. Löfgren, C. Tegner, US 3160662 (1960, 1964 both to Astra).
Properties: Needles, mp 37-38°. bp0.1 159-162°. nD20 1.5298.
Melting point: mp 37-38°
Boiling point: bp0.1 159-162°
Index of refraction: nD20 1.5298
 
Derivative Type: Hydrochloride
CAS Registry Number: 1786-81-8
Manufacturers' Codes: L-67
Trademarks: Citanest (AstraZeneca); Xylonest (AstraZeneca)
Molecular Formula: C13H20N2O.HCl
Molecular Weight: 256.77
Percent Composition: C 60.81%, H 8.24%, N 10.91%, O 6.23%, Cl 13.81%
Properties: Crystals from ethanol + isopropyl ether, mp 167-168°. Readily sol in water.
Melting point: mp 167-168°
 
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).

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