Prolintane
Title: Prolintane
CAS Registry Number: 493-92-5
CAS Name: 1-[1-(Phenylmethyl)butyl]pyrrolidine
Additional Names: 1-(a-propylphenethyl)pyrrolidine; 1-phenyl-2-pyrrolidylpentane; phenylpyrrolidinopentane
Manufacturers' Codes: SP-732
Molecular Formula: C15H23N
Molecular Weight: 217.35
Percent Composition: C 82.89%, H 10.67%, N 6.44%
Literature References: Prepn: GB 807835; Seeger, Kottler, DE 1093799 (1959, 1960 both to Thomae), C.A. 55, 19950c (1961). Pharmacological studies: R. Kadatz, E. Pötzsch, Arzneim.-Forsch. 7, 344 (1957); K. Takagi et al., Oyo Yakuri 5, 5 (1971), C.A. 76, 94575k (1972).
Properties: bp0.5 105°; bp16 153°.
Boiling point: bp0.5 105°; bp16 153°
 
Derivative Type: Hydrochloride
CAS Registry Number: 1211-28-5
Trademarks: Katovit (Thomae); Promotil (Boehringer, Ing.)
Molecular Formula: C15H23N.HCl
Molecular Weight: 253.81
Percent Composition: C 70.98%, H 9.53%, N 5.52%, Cl 13.97%
Properties: Crystals from methyl ether, mp 133-134°. LD50 orally in mice: 257 mg/kg (Kadatz, Pötzsch).
Melting point: mp 133-134°
Toxicity data: LD50 orally in mice: 257 mg/kg (Kadatz, Pötzsch)
 
Therap-Cat: CNS stimulant; antidepressant.
Keywords: Antidepressant; CNS Stimulant.

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