Propyzamide
Title: Propyzamide
CAS Registry Number: 23950-58-5
CAS Name: 3,5-Dichloro-N-(1,1-dimethyl-2-propynyl)benzamide
Additional Names: pronamid
Manufacturers' Codes: RH-315
Trademarks: Kerb (Dow AgroSci.)
Molecular Formula: C12H11Cl2NO
Molecular Weight: 256.13
Percent Composition: C 56.27%, H 4.33%, Cl 27.68%, N 5.47%, O 6.25%
Literature References: Selective pre-emergence herbicide. Prepn: B. W. Horrom et al., ZA 6800090; eidem, US 3534098; US 3640699 (1969, 1970, 1972 all to Rohm & Haas). Activity: K. L. Viste et al., Science 167, 280 (1970); C. Swithenbank et al., J. Agric. Food Chem. 19, 417 (1971). Metabolism: R. Y. Yih et al., Weed Sci. 18, 604 (1970); R. Y. Yih, C. Swithenbank, J. Agric. Food Chem. 19, 314, 320 (1971); J. D. Fisher, ibid. 22, 606 (1974). Carcinogenicity study: M. D. Reuber, Environ. Res. 23, 1 (1980).
Properties: White solid, mp 155-156°. Soly in water at 25°: 15 ppm. Sol in aliphatic, aromatic solvents. Vapor pressure at 25°: 8.5 ´ 10-5 mm Hg. LD50 in male, female rats (mg/kg): 8350, 5620 orally (Viste).
Melting point: mp 155-156°
Toxicity data: LD50 in male, female rats (mg/kg): 8350, 5620 orally (Viste)
Use: Herbicide.

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