Pyrazophos
Title: Pyrazophos
CAS Registry Number: 13457-18-6
CAS Name: 2-[(Diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester
Additional Names: 2-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester, O-ester with O,O-diethyl phosphorothioate
Manufacturers' Codes: HOE-2873
Trademarks: Afugan (Hoechst); Curamil (Hoechst)
Molecular Formula: C14H20N3O5PS
Molecular Weight: 373.36
Percent Composition: C 45.04%, H 5.40%, N 11.25%, O 21.43%, P 8.30%, S 8.59%
Literature References: Systemic fungicide. Prepn: NL 6602131; O. Scherer, H. Mildenberger, US 3632757 (1966, 1972 both to Hoechst). Account of fungicidal properties and toxicity: F. M. Smit, Meded. Rijksfac. Landbouwwet. Gent 34, 763 (1969), C.A. 73, 76038w (1970). In control of rusty spot on peaches: R. H. Daines, Plant Dis. Res. 58, 254 (1974). Effectiveness against powdery mildew: D. J. Butt et al., Ann. Appl. Biol. 75, 217 (1973); F. O. Riordain, Plant Dis. Rep. 58, 12 (1974); R. T. Burchill, M. E. Cook, Plant Pathol. 24, 194 (1975). Enzymatic detection by TLC: G. F. Ernst, F. Schuring, J. Chromatogr. 49, 325 (1970). Absorption and metabolism by plants: S. Gorbach et al., Environ. Qual. Saf. Suppl. 3, 840 (1975).
Properties: Yellow oil, mp 38-40°C. LD50 in rats, marmots, rabbits (mg/kg): 140, 184, 435 orally (Smit).
Melting point: mp 38-40°C
Toxicity data: LD50 in rats, marmots, rabbits (mg/kg): 140, 184, 435 orally (Smit)
Use: Fungicide.

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