Sulfinalol
Title: Sulfinalol
CAS Registry Number: 66264-77-5
CAS Name: 4-Hydroxy-a-[[[3-(4-methoxyphenyl)-1-methylpropyl]amino]methyl]-3-(methylsulfinyl)benzenemethanol
Additional Names: 4-hydroxy-a-[[[3-(p-methoxyphenyl)-1-methylpropyl]amino]methyl]-3-(methylsulfinyl)benzyl alcohol
Molecular Formula: C20H27NO4S
Molecular Weight: 377.50
Percent Composition: C 63.63%, H 7.21%, N 3.71%, O 16.95%, S 8.49%
Literature References: b-Adrenergic blocker. Prepn: R. E. Philion, DE 2728641 (1978 to Sterling), C.A. 90, 137468 (1979). Pharmacological activity profile: P. H. Hernández, Fed. Proc. 38, 738 (1979). Chromatographic determn in human plasma and urine: G. B. Park et al., Anal. Chem. 53, 604 (1981). Metabolism, disposition in animals: D. P. Benziger et al., Drug Metab. Dispos. 9, 493 (1981).
 
Derivative Type: Hydrochloride
CAS Registry Number: 63251-39-8
Manufacturers' Codes: Win-40808-7
Trademarks: Perifadil (Sterling Winthrop)
Molecular Formula: C20H27NO4S.HCl
Molecular Weight: 413.96
Percent Composition: C 58.03%, H 6.82%, N 3.38%, O 15.46%, S 7.75%, Cl 8.56%
Properties: Crystals, mp 172-175°.
Melting point: mp 172-175°
 
Therap-Cat: Antihypertensive.
Keywords: ?Adrenergic Blocker; Antihypertensive; Arylethanolamine Derivatives.

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