Penicillin G Calcium
Title: Penicillin G Calcium
CAS Registry Number: 973-53-5
CAS Name: [2S-(2a,5a,6b)]-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid calcium salt (2:1)
Additional Names: benzylpenicillin calcium; calcium penicillin G; calcium benzylpenicillinate; benzylpenicillinic acid calcium salt
Molecular Formula: C32H34CaN4O8S2
Molecular Weight: 706.84
Percent Composition: C 54.37%, H 4.85%, Ca 5.67%, N 7.93%, O 18.11%, S 9.07%
Line Formula: (C16H17N2O4S)2Ca
Literature References: Antibiotic obtained by extraction of an ether soln of the free acid (prepared from the sodium salt) with satd calcium hydroxide soln to pH 6.5, followed by lyophilizing: Clarke et al., Chemistry of Penicillin (Princeton, 1949) p 88.
Properties: White powder, granules, scales. Freely sol in water, in isotonic sodium chloride soln, in glucose solns. Also sol in alcohol, glycerol, acetone, ethyl acetate, chloroform. Insol in fixed oils, liquid petrolatum. pH of an aq soln contg 20,000 units per ml is 5.0 to 6.5.
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins.
Status: This monograph has been retired and is no longer subject to revision or update.

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