Sucrose Polyester
Title: Sucrose Polyester
Additional Names: Olestra; SPE
Trademarks: Olean (Procter & Gamble)
Literature References: Non-absorbable, non-digestible lipid; noncaloric substitute for fat in foods. Mixture of hexa-, hepta- and octa-fatty acid esters of sucrose. Analysis by gel permeation chromatography: C. G. Birch, F. E. Crowe, J. Am. Oil Chem. Soc. 53, 581 (1976). Effect on absorption of dietary cholesterol in rats: F. H. Mattson et al., J. Nutr. 106, 747 (1976); L. Aust et al., Ann. Nutr. Metab. 25, 255 (1981). Effects as a dietary agent for lowering plasma cholesterol in man: R. W. Fallat et al., Am. J. Clin. Nutr. 29, 1024 (1976); C. J. Glueck et al., ibid. 32, 1636 (1979). Effects on cholesterol metabolism in man: J. R. Crouse, S. M. Grundy, Metab. Clin. Exp. 28, 994 (1979); R. J. Jandacek et al., Am. J. Clin. Nutr. 33, 251 (1980). Caloric dilution study in obese patients: C. J. Glueck et al., ibid. 35, 1352 (1982). Review of properties and clinical safety studies: K. D. Lawson et al., Drug Metab. Rev. 29, 651-703 (1997); of clinical effects on GI functions: J. W. Freston et al., Regul. Toxicol. Pharmacol. 26, 210-218 (1997).
Properties: Smoke point 480°F. Flash point 550°F. Fire point 625°F.
Flash point: Flash point 550°F
Use: Dietary fat replacement in savory snack foods.

Others monographs:
Ammonium SalicylatePavonininsBenzoxonium ChlorideTropicamide
Bismuth IodideRhodium ChlorideLithium CitrateMepivacaine
Fumaric AcidFulvoplumierinAllopregnane-3α,20β-diolLead Oxalate
©2016 DrugLead US FDA&EMEA